Adolore BioTherapeutics Announces Publication of Compelling Preclinical Efficacy and Safety Data Supporting Adolore's Non-opioid Analgesic Gene Therapy, ADLR-1001, For Treatment of Moderate to Severe Chronic Knee Pain Due to Osteoarthritis (OA)

This publication validates Adolore's approach for the intracellular delivery of a non-opioid analgesic minigene to targeted sensory neurons via local administrationData provide a robust preclinical proof-of-concept for this JDNI8-rdHSV-based carbonic anhydrase-8...

Adolore BioTherapeutics Announces Publication Demonstrating Carbonic Anhydrase-8 Gene Therapy (rdHSV-CA8) Decreased Pain-Sensing Neuronal Excitability by Activating Kv7 Voltage-Gated Potassium Channels

Findings highlight the advantages of Adolore’s approach for the delivery of proprietary gene therapy directly to specialized pain-sensing peripheral nerves (nociceptors) that mediate profound analgesia with the potential to address the great unmet need for...